Description

7-Chloro-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Acetic Acid Ethyl Ester is a high-purity, heterocyclic organic building block of significant importance in advanced pharmaceutical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those with pyridopyrimidine core structures.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities (NCEs).
• Agrochemical Synthesis: Serves as a building block for developing advanced crop protection agents and pesticides.
• Material Science Research: Investigated for potential use in creating organic electronic materials and specialty polymers.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	7-Chloro-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Acetic Acid Ethyl Ester
CAS No.	50609-68-2
Molecular Formula	C₁₃H₁₁ClN₂O₃
Molecular Weight	278.69 g/mol
Synonyms	Ethyl 7-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-acetate; 7-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-acetic acid ethyl ester; Ethyl (7-chloro-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl)acetate; 50609-68-2; 7-Chloro-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-acetic acid, ethyl ester; Pyrido[1,2-a]pyrimidine-3-acetic acid, 7-chloro-4-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

Our 7-Chloro-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.