Description

2-Nitro-4,6-Bis-Trifluoromethyl-Phenol is a specialized fluorinated phenolic compound characterized by its unique trifluoromethyl and nitro substituents. This structure makes it a valuable and versatile building block and intermediate in advanced chemical synthesis. It is primarily sought after by the pharmaceutical and agrochemical industries for the development of novel active ingredients, as well as by researchers in material science for creating high-performance polymers and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group contributes to improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functionalizing agent for creating fluorinated polymers, resins, and coatings with superior chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitutions, and other transformations to introduce complex fluorinated phenolic motifs into target molecules.
• Liquid Crystal & Electronic Materials: Investigated for use in the synthesis of components for liquid crystal displays (LCDs) and other electronic materials due to its polar and fluorinated nature.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing specialized dyes and pigments with unique colorfastness and chemical properties.

Basic Information

Item	Details
Product Name	2-Nitro-4,6-Bis-Trifluoromethyl-Phenol
CAS No.	50563-73-0
Molecular Formula	C9H3F6NO3
Molecular Weight	287.12 g/mol
Synonyms	4,6-Bis(trifluoromethyl)-2-nitrophenol; 2-Nitro-α,α,α,α',α',α'-hexafluoro-m-xylen-4-ol; Phenol, 2-nitro-4,6-bis(trifluoromethyl)-; 2-Nitro-4,6-di(trifluoromethyl)phenol; 4,6-Bis(trifluoromethyl)-2-nitro-1-phenol; 2-Nitro-4,6-bis(trifluoromethyl)benzenol; Hexafluoro derivative of 2-nitro-4,6-dimethylphenol
EINECS	Contact for details

Quality Control

Our 2-Nitro-4,6-Bis-Trifluoromethyl-Phenol is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical quality attributes are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.