Description

2,2,2-Trifluoro-1-(4-Fluorophenyl)Ethanol is a versatile fluorinated aromatic alcohol that serves as a critical chiral building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the trifluoromethyl and fluorine substituents, which are essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, as well as by fine chemical manufacturers producing specialty intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Advanced Polymer Monomers: Employed to introduce fluorinated phenyl groups into specialty polymers, enhancing their chemical resistance and surface properties.
• Asymmetric Catalysis Research: A valuable substrate for developing and testing new chiral catalysts and methodologies in academic and industrial laboratories.
• Fluorine Chemistry Building Block: Utilized in exploratory synthesis to create complex fluorinated compounds for material science and electronics applications.

Basic Information

Item	Detail
Product Name	2,2,2-Trifluoro-1-(4-Fluorophenyl)Ethanol
CAS No.	50562-19-1
Molecular Formula	C8H6F4O
Molecular Weight	194.13 g/mol
Synonyms	α,α,α-Trifluoro-4-fluorobenzyl Alcohol; (4-Fluorophenyl)(trifluoromethyl)methanol; 1-(4-Fluorophenyl)-2,2,2-trifluoroethanol; 4-Fluoro-α-(trifluoromethyl)benzyl Alcohol; 2,2,2-Trifluoro-1-(4-fluorophenyl)ethan-1-ol; p-Fluoro-α,α,α-trifluorobenzyl Alcohol; F3C-C(OH)(C6H4F)H; 50562-19-1
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(4-Fluorophenyl)Ethanol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Enantiomeric Excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.