Description

Boc-Ala-D-Glu-Obzl is a protected dipeptide building block of significant importance in synthetic organic and medicinal chemistry. Its primary value lies in enabling the controlled, sequential synthesis of complex peptides and peptidomimetics, particularly those requiring the incorporation of D-glutamic acid. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, where it is used in the development of novel therapeutic agents, enzyme inhibitors, and advanced biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the automated synthesis of custom peptides containing D-glutamic acid residues.
• Pharmaceutical Research: Building block for the development of peptide-based drugs, prodrugs, and diagnostic agents targeting various diseases.
• Enzyme Inhibitor Design: Used to create substrate analogs and transition-state mimics for studying enzyme mechanisms and developing inhibitors.
• Bioconjugation & Labeling: Serves as a starting material for synthesizing peptide tags, linkers, and probes used in bioconjugation chemistry.
• Material Science: Precursor for synthesizing peptide-polymer conjugates and functionalized biomaterials with specific chiral properties.
• Chemical Biology Probes: Employed in the synthesis of activity-based probes and affinity labels to study biological processes.

Basic Information

Product Name	Boc-Ala-D-Glu-Obzl
CAS No.	50515-48-5
Molecular Formula	C₂₀H₂₈N₂O₇
Molecular Weight	408.45 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-alanyl-D-glutamic acid 5-benzyl ester; Boc-L-Ala-D-Glu(OBzl)-OH; Boc-Ala-D-Glu(OBzl); Boc-L-Alanyl-D-glutamic Acid 5-Benzyl Ester; (2R)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]pentanedioic acid 5-benzyl ester; tert-Butoxycarbonyl-L-alanyl-D-glutamic acid γ-benzyl ester; Boc-L-Ala-D-Glu-OBzl; Boc-Ala-ψ[CH₂NH]-D-Glu(OBzl)
EINECS	Contact for details

Quality Control

Our Boc-Ala-D-Glu-Obzl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (D-Glu)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.