Description

Z-Ala-Arg-Oh CAS NO 50465-91-3 is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of the alanine-arginine dipeptide with a free carboxylic acid terminus. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled elongation of peptide chains, particularly in Fmoc/t-Bu chemistry.
• Pharmaceutical Research: Used in the research and development of peptide drugs targeting various diseases, where the Ala-Arg sequence is of interest.
• Bioconjugation: Serves as a linker or spacer molecule in the synthesis of peptide-protein or peptide-small molecule conjugates.
• Enzyme Substrate Synthesis: Employed to create specific substrates for studying protease enzymes like trypsin, which cleaves after arginine residues.
• Biochemical Reagent Production: A raw material for manufacturing high-purity biochemical reagents and reference standards.
• Cosmeceutical Peptide Development: Potential use in the synthesis of bioactive peptides for advanced skincare formulations.

Basic Information

Product Name	Z-Ala-Arg-Oh
CAS No.	50465-91-3
Molecular Formula	C17H26N6O5
Molecular Weight	394.43 g/mol
Synonyms	Nα-Carbobenzoxy-L-alanyl-L-arginine; Z-L-Ala-L-Arg-OH; CBZ-Ala-Arg-OH; N-CBZ-L-alanyl-L-arginine; Benzyloxycarbonyl-L-alanyl-L-arginine; Z-A-R-OH; (2S)-2-[[(2S)-2-[[(benzyloxy)carbonyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid; L-Alanine, N-[(phenylmethoxy)carbonyl]-, L-arginine deriv.
EINECS	Contact for details

Quality Control

Our Z-Ala-Arg-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, optical rotation, and identity confirmation (IR, MS), to ensure it meets the stringent requirements for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]D20	-15.0° to -20.0° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.