Description

3,4-Dihydro-1-(o-Nitrophenyl)-4,4,6-Trimethyl-2(1H)-Pyrimidinethione is a specialized heterocyclic organic compound featuring a pyrimidinethione core substituted with an o-nitrophenyl group. This compound matters as a versatile chemical intermediate and building block for advanced synthesis in pharmaceutical and agrochemical research. Industries requiring the development of novel active ingredients, particularly in medicinal chemistry for drug discovery programs, are the primary users of this high-purity material.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition.
• Agrochemical Research: Used as a building block for developing new active ingredients in crop protection products, such as herbicides or fungicides.
• Chemical Synthesis: Acts as a versatile scaffold for creating complex heterocyclic libraries in combinatorial chemistry and material science.
• Academic & R&D: Employed in university and corporate research laboratories for studying reaction mechanisms and developing new synthetic methodologies.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized colorants and functional materials due to its nitrophenyl and sulfur-containing structure.

Basic Information

Product Name	3,4-Dihydro-1-(o-Nitrophenyl)-4,4,6-Trimethyl-2(1H)-Pyrimidinethione
CAS No.	50403-73-1
Molecular Formula	C₁₃H₁₅N₃O₂S
Molecular Weight	277.34 g/mol
Synonyms	1-(2-Nitrophenyl)-4,4,6-trimethyl-3,4-dihydro-2(1H)-pyrimidinethione; 1-(o-Nitrophenyl)-4,4,6-trimethyl-2-thioxo-1,2,3,4-tetrahydropyrimidine; 2(1H)-Pyrimidinethione, 3,4-dihydro-1-(2-nitrophenyl)-4,4,6-trimethyl-; 4,4,6-Trimethyl-1-(2-nitrophenyl)-3,4-dihydro-2(1H)-pyrimidinethione; 1-(2-Nitrophenyl)-4,4,6-trimethyl-2-thioxo-1,2,3,4-tetrahydropyrimidine
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-1-(o-Nitrophenyl)-4,4,6-Trimethyl-2(1H)-Pyrimidinethione is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.