Description

B-Nor-1-Oxo-5,6-Secocholestan-6-Oic Acid is a high-purity, synthetically derived steroidal acid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its modified cholestane skeleton makes it a valuable building block for the synthesis of novel steroid-based therapeutic agents and complex bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors focused on developing new drug candidates and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel steroid-based drugs targeting hormonal regulation, inflammation, and metabolic disorders.
• Biochemical Research: Used as a reference standard or precursor in metabolic pathway studies and enzyme inhibition assays involving sterol biosynthesis.
• Fine Chemical Synthesis: Serves as a sophisticated starting material for the synthesis of complex, high-value specialty chemicals and molecular probes.
• Academic & Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead compound optimization.

Basic Information

Product Name	B-Nor-1-Oxo-5,6-Secocholestan-6-Oic Acid
CAS No.	50364-98-2
Molecular Formula	C₂₆H₄₂O₃
Molecular Weight	402.62 g/mol
Synonyms	5,6-Secocholestan-6-oic acid, 1-oxo-, B-nor-; 1-Oxo-5,6-secocholestan-6-oic acid, B-nor-; B-Nor-1-oxo-5,6-secocholestan-6-oic acid; 5,6-Seco-B-norcholestan-6-oic acid, 1-oxo-; (5R,8R,9S,10S,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-1,4,16-trione (alternative representation); Steroidal seco-acid intermediate
EINECS	Contact for details

Quality Control

Our B-Nor-1-Oxo-5,6-Secocholestan-6-Oic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.