Description

1-Benzyl-4,6-Dichloro-1H-Pyrazolo[3,4-D]Pyrimidine is a high-purity, heterocyclic organic compound belonging to the pyrazolopyrimidine class, serving as a critical advanced pharmaceutical intermediate. This compound matters for its role as a versatile synthetic building block in the development of targeted therapeutic agents, particularly kinase inhibitors. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for the synthesis of novel drug candidates, leveraging its specific halogenated benzyl structure to modulate biological activity and pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a core scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Agrochemical Development: Serves as a building block for creating novel active ingredients with potential fungicidal or herbicidal activity.
• Academic & Contract Research: Employed in university and CRO settings for exploring new chemical entities and reaction methodologies.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client pipelines.

Basic Information

Product Name	1-Benzyl-4,6-Dichloro-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	50270-30-9
Molecular Formula	C₁₂H₈Cl₂N₄
Molecular Weight	279.12 g/mol
Synonyms	1-Benzyl-4,6-dichloro-1H-pyrazolo[3,4-d]pyrimidine; 4,6-Dichloro-1-benzyl-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 1-benzyl-4,6-dichloro-; 50270-30-9; BDPP; 1-Benzyl-4,6-dichloro-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4,6-Dichloro-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.