Description

Kanamycin, Sulfate (1:1), Monohydrate (8Ci) is a high-purity aminoglycoside antibiotic salt. It is critical for research and development in microbiology and molecular biology, serving as a selective agent. This product is essential for pharmaceutical manufacturers, academic research laboratories, and biotechnology companies requiring a reliable and well-characterized antibiotic for cell culture and genetic engineering applications.

Application

• Cell Culture & Microbiology: Used as a selective antibiotic in bacterial cell culture media to prevent contamination and select for genetically modified organisms.
• Molecular Biology Research: A key component in the preparation of selective agar plates and liquid media for cloning, plasmid amplification, and protein expression studies.
• Pharmaceutical Intermediates: Serves as a starting material or intermediate in the synthesis of more complex antibiotic formulations and drug substances.
• Biochemical Research: Employed in studies of bacterial protein synthesis, antibiotic resistance mechanisms, and aminoglycoside pharmacology.
• Veterinary Medicine: Used in research applications related to the development of treatments for bacterial infections in animals.

Basic Information

Product Name	Kanamycin, Sulfate (1:1), Monohydrate (8Ci)
CAS No.	5965-95-7
Molecular Formula	C18H38N4O15S • H2O
Molecular Weight	582.58 g/mol (monohydrate)
Synonyms	Kanamycin Monosulfate Monohydrate; Kanamycin Sulfate Salt; Kanamycin A Sulfate; Kantrex; Kanasig; Kanamycin Sulfate (1:1); 6-O-(3-Amino-3-deoxy-α-D-glucopyranosyl)-4-O-(6-amino-6-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine Sulfate; Kanamycin Sesquisulfate (common historical name)
EINECS	227-772-2

Quality Control

Our Kanamycin Sulfate Monohydrate is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including identification, purity assay, and impurity profiling to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) with detailed HPLC, NMR, and microbiological potency data are provided to guarantee traceability, consistency, and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC, anhydrous basis)	95.0% - 102.0%
pH (1% solution)	6.0 - 8.0
Water Content (KF)	2.5% - 4.5%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	+112° to +123°
Microbiological Potency	≥ 750 µg/mg (vs. Kanamycin Base)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.