Description

4-(6-Chloro-4-Phenyl-Quinazolin-2-Yl)Piperazine-1-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate with a defined quinazoline-piperazine scaffold. This compound matters as a critical building block for medicinal chemistry research and the synthesis of targeted therapeutic agents. It is primarily needed by R&D laboratories and pharmaceutical manufacturers focused on developing novel kinase inhibitors and other small molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Kinase Inhibitor Research: Used as a core scaffold in the discovery and development of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry: Provides a versatile chemical handle for structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Tool Compound: Employed in biochemical assays to study protein-ligand interactions and cellular signaling mechanisms.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions engaged in cutting-edge drug discovery projects.
• Custom Synthesis: Acts as a starting material for the custom synthesis of more complex, target-specific molecules for client projects.

Basic Information

Product Name	4-(6-Chloro-4-Phenyl-Quinazolin-2-Yl)Piperazine-1-Carbaldehyde
CAS No.	5960-46-3
Molecular Formula	C19H17ClN4O
Molecular Weight	352.82 g/mol
Synonyms	4-(6-Chloro-4-phenylquinazolin-2-yl)piperazine-1-carbaldehyde; 1-Formyl-4-(6-chloro-4-phenyl-2-quinazolinyl)piperazine; 4-(6-Chloro-4-phenylquinazolin-2-yl)piperazine-1-carboxaldehyde; 2-(1-Formyl-4-piperazinyl)-6-chloro-4-phenylquinazoline; 6-Chloro-4-phenyl-2-(1-piperazinyl)quinazoline-1-carbaldehyde; 4-Phenyl-6-chloro-2-(1-formylpiperazin-4-yl)quinazoline; 5960-46-3; 4-(6-Chloro-4-phenyl-2-quinazolinyl)-1-piperazinecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-(6-Chloro-4-Phenyl-Quinazolin-2-Yl)Piperazine-1-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.