Description

D-Glutamine is the D-isomer of the conditionally essential amino acid glutamine, distinguished by its specific stereochemistry. This enantiomeric purity makes it a critical chiral building block and research tool in advanced biochemical and pharmaceutical applications. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers for applications ranging from metabolic studies to the synthesis of specialized peptides and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: As a chiral precursor in the synthesis of novel therapeutic peptides and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in metabolic pathway studies, enzyme-substrate specificity investigations, and as a component in defined cell culture media.
• Nutritional Science Studies: Employed in comparative research to study the differential metabolism and effects of D- versus L-amino acid isomers.
• Fine Chemical Synthesis: Serves as a key chiral intermediate for producing complex organic molecules and specialty chemicals.
• Microbiology: Can be used in specialized microbial growth media for selective bacterial culture and metabolic research.

Basic Information

Product Name	D-Glutamine
CAS No.	5959-95-5
Molecular Formula	C5H10N2O3
Molecular Weight	146.14 g/mol
Synonyms	(R)-2,5-Diamino-5-oxopentanoic acid; D-2-Aminoglutaramic acid; (R)-Glutamine; D-Gln; H-D-Gln-OH; (2R)-2-Amino-4-carbamoylbutanoic acid; D-Glutamic acid 5-amide
EINECS	227-736-3

Quality Control

Our D-Glutamine is produced under strict quality management systems to ensure high enantiomeric purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess determination, identity confirmation by IR spectroscopy, and purity assessment. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (D-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition (Sulfated Ash)	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation [α]20/D	+6.5° to +8.0° (c=2 in 1N HCl)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.