Description

3'-o-L-Phenylalanyladenosine is a chemically modified nucleoside derivative where an L-phenylalanine residue is esterified to the 3'-hydroxyl group of adenosine. This structural modification is of significant interest in biochemical research and pharmaceutical development, particularly for studying nucleotide metabolism and enzyme interactions. It serves as a valuable intermediate or reference standard for researchers in medicinal chemistry and molecular biology. The compound is primarily utilized by professionals in pharmaceutical R&D, academic institutions, and biotechnology companies focused on nucleoside-based therapeutics and probe development.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel nucleoside-based drug candidates and prodrugs.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies to investigate adenosine-processing enzymes and transferases.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore the impact of amino acid conjugation on nucleoside activity.
• Probe Development: Utilized in the creation of molecular probes for studying biological pathways and cellular uptake mechanisms.
• Academic Research: Supports fundamental research in universities and institutes focusing on nucleotide chemistry and bio-conjugation techniques.

Basic Information

Product Name	3'-o-L-Phenylalanyladenosine
CAS No.	5956-81-0
Molecular Formula	C20H23N7O5
Molecular Weight	441.44 g/mol
Synonyms	Adenosine, 3'-O-L-phenylalanyl-; 3'-O-(L-Phenylalanyl)adenosine; L-Phenylalanine, 3'-ester with adenosine; 3'-O-Phenylalanyladenosine; 3'-O-L-Phenylalanyladenosine; 3'-O-(L-Phenylalanyl)adenosine; 3'-O-L-Phenylalanyl-adenosine; 3'-O-Phenylalanyl-adenosine
EINECS	Contact for details

Quality Control

Our 3'-o-L-Phenylalanyladenosine is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for identity, purity, and related substances. We are committed to supply reliability and consistent quality, supporting your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.