Description

Ethyl 4-(4-Hydroxy-3-Methoxyphenyl)-2-Mercapto-6-Methyl-1,4-Dihydropyrimidine-5-Carboxylate is a specialized dihydropyrimidine derivative, a class of compounds known for their significant biological and pharmaceutical relevance. This compound serves as a key synthetic intermediate and a valuable scaffold in medicinal chemistry research for developing novel therapeutic agents. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in cardiovascular and neurological research.
• Medicinal Chemistry Scaffold: Used to explore structure-activity relationships (SAR) for developing new enzyme inhibitors and receptor modulators.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides due to its heterocyclic core.
• Chemical Biology Probe: Utilized in biochemical assays to study specific biological pathways and protein interactions.
• Academic & Institutional R&D: Employed in universities and research institutes for synthetic methodology development and novel compound library generation.
• Fine Chemical Synthesis: Acts as a specialized intermediate for producing complex, high-value organic molecules.

Basic Information

Product Name	Ethyl 4-(4-Hydroxy-3-Methoxyphenyl)-2-Mercapto-6-Methyl-1,4-Dihydropyrimidine-5-Carboxylate
CAS No.	5948-75-4
Molecular Formula	C15H18N2O4S
Molecular Weight	322.38 g/mol
Synonyms	Ethyl 4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-3,4-dihydropyrimidine-5-carboxylate; 5-Carbethoxy-4-(4-hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine; 4-(4-Hydroxy-3-methoxyphenyl)-2-mercapto-6-methyl-1,4-dihydropyrimidine-5-carboxylic Acid Ethyl Ester; 2-Mercapto-4-(4-hydroxy-3-methoxyphenyl)-6-methyl-1,4-dihydropyrimidine-5-carboxylic Acid Ethyl Ester; DHPM derivative; Biginelli adduct derivative; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for key parameters. Our quality management system supports the needs of research and development under cGMP-like controls where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.