Description

Ethyl 4-Methyl-2-Oxo-6-Thiophen-2-Yl-3,6-Dihydro-1H-Pyrimidine-5-Carboxylate CAS NO 5948-72-1 is a high-purity, heterocyclic organic compound featuring a fused pyrimidine-thiophene core structure. This advanced pharmaceutical intermediate is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs) and complex molecules for medicinal chemistry research. It is primarily sought after by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly in oncology and antiviral therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel bioactive compounds.
• Fine Chemical Synthesis: Serves as a precursor for synthesizing more complex heterocyclic compounds and specialty chemicals.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and discovery chemistry projects.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents and pesticides.

Basic Information

Item	Detail
Product Name	Ethyl 4-Methyl-2-Oxo-6-Thiophen-2-Yl-3,6-Dihydro-1H-Pyrimidine-5-Carboxylate
CAS No.	5948-72-1
Molecular Formula	C₁₂H₁₂N₂O₃S
Molecular Weight	264.30 g/mol
Synonyms	Ethyl 4-methyl-2-oxo-6-(thiophen-2-yl)-3,6-dihydro-1H-pyrimidine-5-carboxylate; 5-Carbethoxy-4-methyl-6-(2-thienyl)-3,4-dihydro-2(1H)-pyrimidinone; 6-(2-Thienyl)-4-methyl-2-oxo-1,4,5,6-tetrahydropyrimidine-5-carboxylic Acid Ethyl Ester; 1,4,5,6-Tetrahydro-4-methyl-6-(2-thienyl)-2(3H)-pyrimidinone-5-carboxylic Acid Ethyl Ester; 5948-72-1; 6-(Thiophen-2-yl)-4-methyl-2-oxo-1,4,5,6-tetrahydropyrimidine-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Methyl-2-Oxo-6-Thiophen-2-Yl-3,6-Dihydro-1H-Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete analytical data are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.