Description

6-Methyl-2,4-Dioxo-1-Phenyl-1,2,3,4-Tetrahydro-Pyrimidine-5-Carbonitrile is a high-value heterocyclic organic compound with a fused pyrimidine-dione structure. This versatile chemical intermediate is critical for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the creation of new active ingredients for crop protection products, leveraging its structural complexity.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, enabling the construction of diverse chemical libraries for screening.
• Material Science: Potential intermediate in the development of specialty polymers or organic electronic materials due to its conjugated system.
• Academic & Contract Research: Essential for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	6-Methyl-2,4-Dioxo-1-Phenyl-1,2,3,4-Tetrahydro-Pyrimidine-5-Carbonitrile
CAS No.	5900-42-5
Molecular Formula	C₁₂H₉N₃O₂
Molecular Weight	227.22 g/mol
Synonyms	5-Cyano-6-methyl-1-phenyl-1,2,3,4-tetrahydro-2,4-pyrimidinedione; 6-Methyl-1-phenyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile; 5-Cyano-6-methyl-1-phenyl-1H-pyrimidine-2,4(3H,5H)-dione; 1-Phenyl-6-methyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinecarbonitrile; 6-Methyl-1-phenylbarbituric acid-5-carbonitrile; DHPM Carbonitrile Derivative
EINECS	227-597-8

Quality Control

Our 6-Methyl-2,4-Dioxo-1-Phenyl-1,2,3,4-Tetrahydro-Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.