Description

Z-Gly-Pro-Ala-OH is a protected tripeptide derivative, widely utilized as a key building block in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is particularly valuable for the pharmaceutical, biotechnology, and life sciences industries involved in developing therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediates: A crucial building block for the synthesis of longer, biologically active peptide sequences for drug discovery and development.
• Biochemical Research: Used in studies of enzyme-substrate interactions, peptide structure-activity relationships (SAR), and proteomics.
• Solid-Phase Peptide Synthesis (SPPS): Serves as a protected fragment for the sequential assembly of custom peptides on resin supports.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening against biological targets.
• Protease Substrate Analogues: Useful in the design and synthesis of inhibitors or substrates for proteolytic enzymes.
• Cosmetic Peptide Synthesis: A precursor for certain bioactive peptides used in advanced skincare and cosmetic formulations.

Basic Information

Product Name	Z-Gly-Pro-Ala-OH
CAS No.	5891-41-8
Molecular Formula	C19H25N3O7
Molecular Weight	407.42 g/mol
Synonyms	Z-Gly-Pro-Ala; Z-Gly-Pro-Ala-OH; N-Carbobenzoxy-Glycyl-L-Prolyl-L-Alanine; N-Cbz-Glycyl-L-Prolyl-L-Alanine; Cbz-Gly-Pro-Ala-OH; Benzyloxycarbonyl-Glycyl-Prolyl-Alanine; Nα-Cbz-Gly-L-Pro-L-Ala-OH; Glycylprolylalanine N-carboxy anhydride derivative
EINECS	Contact for details

Quality Control

Our Z-Gly-Pro-Ala-OH is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric integrity, and identity confirmation by spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.