Description

D-Ala-Ala-Ala is a high-purity, synthetic tripeptide composed of three D-alanine amino acid residues. This specific stereochemistry makes it a valuable chiral building block and a critical reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers working on peptide-based therapeutics, enzyme substrates, and metabolic studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis of novel peptide drugs and protease inhibitors.
• Biochemical Studies: Used as a substrate or inhibitor in enzymatic assays to study protease specificity and kinetics, leveraging its D-configuration for stability against common L-specific enzymes.
• Chiral Synthesis: Acts as a valuable chiral building block or auxiliary in asymmetric synthesis for constructing complex molecules with defined stereochemistry.
• Academic Research: Employed in universities and research institutes for fundamental studies in peptide chemistry, molecular recognition, and structural biology.
• Quality Control & Analytics: Functions as a high-purity calibration standard in analytical laboratories for methods like HPLC and mass spectrometry to ensure accuracy in peptide analysis.

Basic Information

Product Name	D-Ala-Ala-Ala
CAS No.	5874-89-5
Molecular Formula	C9H17N3O4
Molecular Weight	231.25 g/mol
Synonyms	D-Alanine-D-alanine-D-alanine; (R)-Alanyl-(R)-alanyl-(R)-alanine; H-D-Ala-D-Ala-D-Ala-OH; D-Trialanine; D-AAA; Tri-D-alanine; D-Ala-D-Ala-D-Ala; N-(N-(D-Alanyl)-D-alanyl)-D-alanine
EINECS	Contact for details

Quality Control

Our D-Ala-Ala-Ala is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and mass spectrometry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.