Description

H-Ala-D-Ala-Ala-Oh is a synthetic tripeptide sequence featuring a D-alanine residue, a structural motif of significant interest in biochemical research. This compound serves as a crucial building block and model substrate for studying enzyme specificity, peptide stability, and resistance mechanisms. It is primarily utilized by research institutions and pharmaceutical developers working in the fields of antibiotic research, peptidomimetic drug design, and enzymology.

Application

• Biochemical Research: Used as a model substrate for studying the activity and inhibition of enzymes like DD-peptidases and bacterial transpeptidases.
• Antibiotic Development: Serves as a key intermediate or probe in research targeting bacterial cell wall biosynthesis and β-lactam resistance mechanisms.
• Peptide Synthesis: Acts as a protected tripeptide building block for the solid-phase or solution-phase synthesis of more complex peptide sequences.
• Enzyme Specificity Studies: Employed to investigate the stereochemical preferences and catalytic mechanisms of proteases and peptidases.
• Pharmaceutical Intermediates: Potential use as a chiral intermediate in the development of novel therapeutic agents and peptidomimetics.
• Academic & Industrial R&D: Fundamental tool in microbiology, medicinal chemistry, and structural biology research programs.

Basic Information

Product Name	H-Ala-D-Ala-Ala-Oh
CAS No.	5874-86-2
Molecular Formula	C9H17N3O4
Molecular Weight	231.25 g/mol
Synonyms	Ala-D-Ala-Ala; L-Alanyl-D-alanyl-L-alanine; H-L-Ala-D-Ala-L-Ala-OH; Tripeptide Ala-D-Ala-Ala; (S)-2-((R)-2-Aminopropanamido)propanoic acid; N-L-Alanyl-D-alanyl-L-alanine; D-Alanine containing tripeptide; AAD tripeptide
EINECS	Contact for details

Quality Control

Our H-Ala-D-Ala-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via mass spectrometry and NMR. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0% ee (D-Ala)
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.