Description

5-(2-Thienyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating thienyl and trifluoromethyl groups. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel drug candidates with potential for enhanced metabolic stability and target binding affinity. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged pyrazolopyrimidine scaffold.
• Agrochemical Development: Serves as a building block for creating new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of chemical probes to study biological pathways and protein function.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthesis projects.
• Library Synthesis: A valuable component for generating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	5-(2-Thienyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid
CAS No.	5841-98-5
Molecular Formula	C12H6F3N3O2S
Molecular Weight	313.26 g/mol
Synonyms	5-(Thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 5-(2-Thienyl)-7-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid; 5841-98-5; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 5-(2-thienyl)-7-(trifluoromethyl)-; 7-(Trifluoromethyl)-5-(2-thienyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(2-Thienyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets exacting research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.