Description

Magnesium 2-Oxopyrrolidine-5-Carboxylate is the magnesium salt of L-pyroglutamic acid, a key derivative of the amino acid L-glutamic acid. This compound is valued for its role as a stable and bioavailable source of magnesium and pyroglutamate, offering enhanced stability and handling properties compared to the free acid. It is primarily utilized in the pharmaceutical and nutraceutical industries for the formulation of dietary supplements, nootropic agents, and as an intermediate in the synthesis of more complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediates: A key building block in the synthesis of racetam-class nootropic drugs and other neuroactive pharmaceutical compounds.
• Dietary Supplements: Used as a source of bioavailable magnesium and pyroglutamic acid in nutritional and cognitive health supplement formulations.
• Cosmetic Ingredients: Incorporated into skincare products for its potential moisturizing and skin-conditioning properties.
• Biochemical Research: Serves as a reagent and standard in metabolic pathway studies and neurological research.
• Food Fortification: Potential application in functional foods and beverages as a nutrient enhancer, subject to regulatory approval.

Basic Information

Product Name	Magnesium 2-Oxopyrrolidine-5-Carboxylate
CAS No.	5819-47-6
Molecular Formula	C10H12MgN2O6 (for the dihydrate common form)
Molecular Weight	304.53 g/mol (Dihydrate)
Synonyms	Magnesium L-Pyroglutamate; Magnesium (5-Oxo-L-prolinate); L-Pyroglutamic Acid Magnesium Salt; Magnesium 5-Oxoproline; PCA Magnesium Salt; Magnesium Pyrrolidone Carboxylate; L-2-Pyrrolidone-5-carboxylic acid magnesium salt
EINECS	Contact for details

Quality Control

Our Magnesium 2-Oxopyrrolidine-5-Carboxylate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, heavy metals, and related substances. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent caking or degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (on dried basis)	98.0% - 102.0%
Loss on Drying	≤ 12.0% (typically ~11.8% for dihydrate)
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	[α]20/D: -10.0° to -14.0° (c=1 in H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.