Description

3-Hydroxy-L-Tyrosine Hydrochloride is a high-purity, synthetically derived amino acid derivative, serving as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. Its primary value lies in its role as a precursor for the production of catecholamines and other bioactive compounds, offering researchers and manufacturers a reliable building block with defined stereochemistry. This product is essential for pharmaceutical R&D, fine chemical synthesis, and as a reference standard in analytical laboratories.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of L-DOPA (Levodopa) and related catecholamine drugs for neurological disorders.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, metabolic pathway analysis, and neurotransmitter research.
• Fine Chemical Synthesis: Building block for the preparation of complex organic molecules, peptidomimetics, and specialized chiral compounds.
• Reference Standard: High-purity material for use in quality control (QC) and analytical method development in pharmaceutical and contract research organizations (CROs).
• Nutraceutical Development: Investigated for potential applications in dietary supplements targeting cognitive and metabolic health.

Basic Information

Product Name	3-Hydroxy-L-Tyrosine Hydrochloride
CAS No.	5796-14-5
Molecular Formula	C9H12NO4 • HCl
Molecular Weight	233.66 g/mol (Free base: 197.19 g/mol)
Synonyms	L-DOPA Hydrochloride; Levodopa Hydrochloride; (2S)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid hydrochloride; 3,4-Dihydroxy-L-phenylalanine hydrochloride; 3-Hydroxy-L-tyrosine HCl; (-)-DOPA Hydrochloride; 3,4-Dihydroxyphenyl-L-alanine hydrochloride
EINECS	227-320-3

Quality Control

Our 3-Hydroxy-L-Tyrosine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets stringent specifications for pharmaceutical and research applications. Certificates of Analysis (COA) documenting identity, purity, and all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Optical Rotation [α]20/D	-10.0° to -12.0° (c=1 in 1N HCl)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.