Description

2,5-Dichloro-4-Methoxypyrimidine is a versatile halogenated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its reactive chlorine atoms and methoxy group, which allow for selective functionalization to create complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and liquid crystals due to its aromatic heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions where required.

Basic Information

Product Name	2,5-Dichloro-4-Methoxypyrimidine
CAS No.	5750-74-3
Molecular Formula	C5H4Cl2N2O
Molecular Weight	179.00 g/mol
Synonyms	4-Methoxy-2,5-dichloropyrimidine; 2,5-Dichloro-4-methoxypyrimidine; 4-Methoxypyrimidine, 2,5-dichloro-; 2,5-Dichloro-4-pyrimidinol methyl ether
EINECS	Contact for details

Quality Control

Our 2,5-Dichloro-4-Methoxypyrimidine is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with ICH guidelines, and we can support projects requiring material suitable for use in GMP-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.