Description

L-Serine-Ul-14C is a uniformly carbon-14 labeled form of the essential amino acid L-serine, identified by CAS No. 5692-15-9. This isotopically labeled compound is a critical tool for advanced metabolic and biochemical research, enabling precise tracking of serine's metabolic pathways. It is indispensable for scientists and researchers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity tracers for studies in drug metabolism, protein synthesis, and cellular function.

Application

• Metabolic Pathway Tracing: Used as a radiolabeled tracer to study the biosynthesis and catabolism of serine, glycine, and related metabolites in vivo and in vitro.
• Drug Metabolism and Pharmacokinetics (DMPK): Essential for ADME (Absorption, Distribution, Metabolism, Excretion) studies to track the metabolic fate of new drug candidates.
• Biochemical Research: Employed in enzymatic assays and studies of one-carbon metabolism, folate cycle, and phospholipid biosynthesis.
• Protein Labeling Studies: Facilitates research into protein synthesis, folding, and turnover by incorporating the labeled amino acid into newly synthesized proteins.
• Diagnostic Agent Development: Serves as a precursor in the research and development of novel diagnostic imaging agents.
• Nutritional and Biomedical Research: Applied in studies investigating serine's role in neurological function, cell proliferation, and immune response.

Basic Information

Product Name	L-Serine-Ul-14C
CAS No.	5692-15-9
Molecular Formula	C3H714CNO3 *
Molecular Weight	~108.1 g/mol (based on 14C label)
Synonyms	(2S)-2-Amino-3-hydroxypropanoic acid (U-14C); L-Serine (U-14C); Serine (U-14C); (S)-Serine (U-14C); 14C-Serine; Uniformly Labeled Carbon-14 L-Serine; L-2-Amino-3-hydroxypropionic acid (U-14C)
EINECS	Contact for details

* Formula indicates uniform labeling with Carbon-14 across all carbon atoms.

Quality Control

Every batch of L-Serine-Ul-14C is manufactured and analyzed under strict quality systems to ensure the highest standards of radiochemical purity, chemical purity, and specific activity. Our quality commitment includes comprehensive testing via HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, specific activity (mCi/mmol or GBq/mmol), and solvent content to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep the container sealed under an inert atmosphere in a dedicated freezer. Follow all applicable laboratory safety and radiation safety protocols for handling and disposal.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 98%
Chemical Purity (HPLC)	≥ 98%
Specific Activity	Customizable (e.g., 50-150 mCi/mmol)
Solvent (if present)	Specified on COA
Radioisotopic Content	> 99% Carbon-14

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.