Description

cis-2-Amino-1-Cyclohexanecarboxylic Acid is a non-proteinogenic cyclic amino acid derivative, serving as a crucial chiral building block in advanced organic synthesis. Its constrained cyclohexane ring structure provides unique stereochemical and conformational properties, enabling the development of novel compounds with enhanced biological activity and stability. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors, particularly for creating peptidomimetics, active pharmaceutical ingredients (APIs), and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Peptidomimetics & Constrained Peptide Design: Used to introduce conformational rigidity into peptide backbones, improving metabolic stability and receptor selectivity.
• Agrochemical Synthesis: Serves as a precursor for developing chiral herbicides, fungicides, and plant growth regulators with higher efficacy.
• Catalyst & Ligand Development: Employed in the preparation of chiral ligands for asymmetric catalysis, such as hydrogenation and C-C bond formation reactions.
• Biochemical Research: Utilized as a probe or substrate in enzymatic studies to investigate amino acid metabolism and transport mechanisms.
• Specialty Polymers: Incorporated into polyamides or other polymers to impart specific chiral or structural characteristics.

Basic Information

Product Name	cis-2-Amino-1-Cyclohexanecarboxylic Acid
CAS No.	5691-20-3
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1R,2S)-2-Aminocyclohexanecarboxylic acid; cis-2-Aminocyclohexanecarboxylic acid; (1R,2S)-2-Amino-1-cyclohexanecarboxylic acid; cis-ACHC; cis-2-ACHC; cis-2-Aminocyclohexane-1-carboxylic acid; (1R,2S)-ACHC; L-cis-2-Aminocyclohexanecarboxylic acid
EINECS	227-146-3

Quality Control

Our cis-2-Amino-1-Cyclohexanecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.