Description

4-Acetylamino-Naphthalene-1-Sulfonyl Chloride is a key sulfonyl chloride derivative used as a versatile building block in advanced organic synthesis. Its primary value lies in its reactive sulfonyl chloride group, which facilitates the introduction of the sulfonamide moiety into target molecules, a critical step in developing compounds with specific biological or material properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those containing sulfonamide pharmacophores for therapeutic applications.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the sulfonamide group contributes to biological activity.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized naphthalene-based dyes and colorants.
• Material Science Research: Employed in the creation of functional polymers and advanced organic materials that require sulfonamide linkages.
• Bioconjugation and Probe Development: Useful in biochemical research for labeling proteins or other biomolecules due to its reactive sulfonyl chloride group.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for fine chemical companies offering bespoke synthesis services.

Basic Information

Product Name	4-Acetylamino-Naphthalene-1-Sulfonyl Chloride
CAS No.	5690-20-0
Molecular Formula	C₁₂H₁₀ClNO₃S
Molecular Weight	283.73 g/mol
Synonyms	1-Naphthalenesulfonyl chloride, 4-(acetylamino)-; 4-Acetamido-1-naphthalenesulfonyl chloride; N-Acetyl-4-amino-1-naphthalenesulfonyl chloride; 4-Acetamidonaphthalene-1-sulfonyl chloride; 1-Sulfonyl chloride-4-acetamidonaphthalene; 4-(Acetylamino)naphthalene-1-sulfonyl chloride; NSC 403107
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for fine chemical intermediates. Each batch is analyzed to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific test results are available upon request. We adhere to strict in-house quality protocols to guarantee the reliability required for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.