Description

Cyclo(Tyr-Pro) CAS NO 5654-84-2 is a cyclic dipeptide, also known as a diketopiperazine (DKP), formed from the amino acids tyrosine and proline. This compound is of significant interest in pharmaceutical research and development due to its role as a potential bioactive scaffold and a metabolite of larger peptide drugs. It serves as a critical intermediate and reference standard for researchers in medicinal chemistry, peptide synthesis, and metabolic studies. Industries focused on drug discovery, analytical testing, and high-purity biochemicals are the primary users of this specialized material.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification in analytical methods like HPLC and LC-MS for drug development and quality control.
• Medicinal Chemistry Scaffold: Serves as a core structure for designing and synthesizing novel drug candidates due to the bioactive properties of diketopiperazines.
• Metabolite Studies: Employed in research to study the metabolic pathways and stability of tyrosine-proline containing peptide therapeutics.
• Biochemical Research: Utilized as a tool compound in biochemical assays to investigate enzyme inhibition, receptor binding, or other biological interactions.
• Peptide Synthesis Intermediate: Acts as a building block or protected derivative in the solid-phase or solution-phase synthesis of more complex peptides.

Basic Information

Product Name	Cyclo(Tyr-Pro)
CAS No.	5654-84-2
Molecular Formula	C14H16N2O3
Molecular Weight	260.29 g/mol
Synonyms	Cyclo(L-Tyrosyl-L-prolyl); L-Tyrosyl-L-proline anhydride; 3,6-Bis(4-hydroxyphenyl)-2,5-piperazinedione; Cyclo(L-Tyr-L-Pro); DKPs; Diketopiperazine; 2,5-Diketopiperazine derivative; (3S,6S)-3-(4-Hydroxybenzyl)-6-methylpiperazine-2,5-dione
EINECS	Contact for details

Quality Control

Our Cyclo(Tyr-Pro) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.