Description

Cyclo(Valylvalyl) CAS NO 5625-44-5 is a synthetic cyclic dipeptide, specifically a diketopiperazine (DKP) derived from two valine amino acids. This compound is valued for its role as a key building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for developing novel therapeutic agents and studying peptide conformation.

Application

• Pharmaceutical Intermediate: A crucial scaffold for the synthesis of more complex peptide-based drugs and bioactive molecules.
• Protease Inhibitor Research: Used in studies targeting enzymes like dipeptidyl peptidase IV (DPP-IV) due to its structural mimicry of peptide substrates.
• Conformational Studies: Serves as a model compound for investigating the structural and folding properties of cyclic peptides.
• Combinatorial Chemistry: Employed as a core structure in libraries for high-throughput screening to discover new lead compounds.
• Biochemical Tool: Utilized in academic and industrial research to explore cell signaling pathways and protein-protein interactions.
• Fine Chemical Synthesis: Acts as a chiral building block for the asymmetric synthesis of non-peptidic compounds with potential biological activity.

Basic Information

Product Name	Cyclo(Valylvalyl)
CAS No.	5625-44-5
Molecular Formula	C10H18N2O2
Molecular Weight	198.26 g/mol
Synonyms	Cyclo(L-valyl-L-valyl); Cyclo(Val-Val); (3S,6S)-3,6-Diisopropyl-2,5-piperazinedione; L-Valyl-L-valine anhydride; Diketopiperazine of L-valine; (S,S)-Cyclo(valylvalyl); 2,5-Diketopiperazine, 3,6-bis(1-methylethyl)-, (3S,6S)-; Valine DKP
EINECS	227-062-4

Quality Control

Our Cyclo(Valylvalyl) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.