Description

Cholecystokinin Fragment 30-33 Amide Hydrochloride is a synthetic tetrapeptide amide derivative of the gastrointestinal hormone cholecystokinin (CCK). This high-purity peptide fragment is a critical research tool for studying CCK receptor interactions, digestive physiology, and neurological signaling pathways. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in metabolic and neurobiological studies.

Application

• Biomedical Research: A key reference standard and active agent in studies investigating the role of cholecystokinin in appetite regulation, pancreatic secretion, and gallbladder contraction.
• Pharmacological Assay Development: Used for the validation and calibration of bioassays and receptor binding studies targeting CCK-A and CCK-B receptors.
• Neuroscience Research: Employed in exploring the neuromodulatory functions of CCK fragments in the central and peripheral nervous systems.
• Drug Discovery & Development: Serves as a starting material or intermediate for the synthesis of novel peptide-based therapeutics targeting metabolic disorders.
• Academic & Clinical Studies: Utilized in university and hospital laboratories for fundamental research into gastrointestinal hormones and their fragments.

Basic Information

Product Name	Cholecystokinin Fragment 30-33 Amide Hydrochloride
CAS No.	5609-49-4
Molecular Formula	C23H34N6O6 • HCl
Molecular Weight	526.02 g/mol (as free base)
Synonyms	CCK Fragment 30-33 Amide HCl; CCK-4 Amide Hydrochloride; Cholecystokinin (30-33) Amide Hydrochloride; Trp-Met-Asp-Phe-NH2 • HCl; Tetragastrin Amide Hydrochloride; Boc-Trp-Met-Asp-Phe-NH2 HCl (precursor form); WMDF-NH2 • HCl
EINECS	Contact for details

Quality Control

Our Cholecystokinin Fragment 30-33 Amide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and specific tests for residual solvents and moisture content. We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with rigorous research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Acetate Content (IC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.