Description

4-Amino-5-Bromo-1-(Tetrahydro-2H-Pyran-2-Yl)Pyrimidin-2(1H)-One is a high-value, protected pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both amino and bromo substituents on the pyrimidine ring, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical development companies for the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs and other antiviral or anticancer drug candidates.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with specific modes of action.
• Chemical Synthesis: Versatile scaffold for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new chemical entities.
• Material Science: Potential intermediate for creating specialty polymers or organic electronic materials.

Basic Information

Product Name	4-Amino-5-Bromo-1-(Tetrahydro-2H-Pyran-2-Yl)Pyrimidin-2(1H)-One
CAS No.	5580-94-9
Molecular Formula	C9H12BrN3O2
Molecular Weight	274.12 g/mol
Synonyms	4-Amino-5-bromo-1-(tetrahydro-2H-pyran-2-yl)-2(1H)-pyrimidinone; 4-Amino-5-bromo-1-(tetrahydropyran-2-yl)pyrimidin-2(1H)-one; 5-Bromo-4-amino-1-(tetrahydro-2H-pyran-2-yl)pyrimidin-2(1H)-one; THP-protected 5-bromocytosine derivative; 1-(Tetrahydro-2H-pyran-2-yl)-5-bromocytosine; 5580-94-9; 4-Amino-5-bromo-1-(2-tetrahydropyranyl)-2(1H)-pyrimidinone
EINECS	Contact for details

Quality Control

Our production of 4-Amino-5-Bromo-1-(Tetrahydro-2H-Pyran-2-Yl)Pyrimidin-2(1H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.