Description

Acth (1-16) is a synthetic peptide fragment corresponding to the first sixteen amino acids of the adrenocorticotropic hormone (ACTH). This compound is a key research tool for studying the structure-activity relationships of ACTH and its role in stimulating cortisol production. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies focused on endocrinology, peptide chemistry, and therapeutic development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the physiological functions and metabolic pathways of ACTH.
• Peptide Chemistry Studies: Serves as a model compound for synthesizing, modifying, and analyzing peptide sequences and their biological activity.
• Pharmaceutical Development: Employed in early-stage drug discovery for screening and developing novel therapeutics targeting the melanocortin system.
• Endocrinology Assays: Acts as a critical component in in vitro bioassays to measure adrenal cortex stimulation and corticosteroidogenesis.
• Biochemical Reagent: Functions as a high-purity biochemical reagent for calibrating analytical instruments like HPLC and mass spectrometers in quality control labs.

Basic Information

Product Name	Acth (1-16)
CAS No.	5576-42-1
Molecular Formula	C₈₀H₁₂₃N₂₁O₂₄S
Molecular Weight	1786.0 g/mol
Synonyms	ACTH (1-16); Adrenocorticotropic Hormone (1-16); Corticotropin (1-16); Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-OH; ACTH 1-16; α-MSH/ACTH (1-16)
EINECS	Contact for details

Quality Control

Our Acth (1-16) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets rigorous research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.