Description

4-Chloro-3-Fluorobenzaldehyde is a versatile halogenated benzaldehyde derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and insecticides, leveraging the chloro and fluoro substituents for enhanced bioactivity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized organic molecules used in electronic displays and lighting technologies.
• Polymer & Resin Modifiers: Incorporated into polymer chains to alter physical properties such as thermal stability, solubility, and refractive index.
• Dyestuff & Pigment Intermediate: Utilized in the production of complex dyes and high-performance pigments for industrial applications.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for creating biaryl structures common in material science.

Basic Information

Product Name	4-Chloro-3-Fluorobenzaldehyde
CAS No.	5527-95-7
Molecular Formula	C7H4ClFO
Molecular Weight	158.56 g/mol
Synonyms	3-Fluoro-4-chlorobenzaldehyde; 4-Chloro-3-fluorobenzenecarboxaldehyde; 3-Fluoro-4-chlorobenzenecarbaldehyde; Benzaldehyde, 4-chloro-3-fluoro-; 4-Chloro-3-fluorobenzaldehyde; 4-Chloro-3-fluorobenzene-1-carbaldehyde; 3-Fluoro-4-chlorobenzaldehyde; 4-Chloro-3-fluoro-benzaldehyde
EINECS	226-869-6

Quality Control

Our 4-Chloro-3-Fluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	45 - 48 °C
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.