Description

Dihydrostreptomycin Sulfate is a semi-synthetic aminoglycoside antibiotic derived from streptomycin. It is valued for its broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, and its stability in various formulations. This product is essential for manufacturers in the pharmaceutical and veterinary medicine industries, where it is used in the production of injectable solutions and medicated feed additives. Its reliable efficacy makes it a key component in combating bacterial infections in both human and animal health sectors.

Application

• Active Pharmaceutical Ingredient (API) in injectable antibiotic formulations.
• Key component in veterinary medicines for the treatment of bacterial infections in livestock and poultry.
• Used in research and development as a selective agent in cell culture media.
• Incorporated into medicated animal feed premixes for prophylactic and therapeutic purposes.
• Reference standard in analytical laboratories for quality control and method validation.
• Intermediate in the synthesis of more complex pharmaceutical compounds.

Basic Information

Product Name	Dihydrostreptomycin Sulfate
CAS No.	5490-27-7
Molecular Formula	C21H41N7O12 · xH2SO4
Molecular Weight	583.6 g/mol (base)
Synonyms	Dihydrostreptomycin Sesquisulfate; Streptomycin Dihydro Sulfate; DHS; Dihydrostreptomycin Acid Sulfate; 2-(1,1-Diguanidino-2-L-streptamin-o-4,5-dihydroxy-6-hydroxymethyl-tetrahydropyran-3-yloxy)-5-deoxy-3-C-formyl-L-lyxofuranosyl-(1-4)-N3,N3-diamino-D-ribose Sulfate; Antibiotic 18-34 Sulfate
EINECS	226-826-1

Quality Control

Our Dihydrostreptomycin Sulfate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and veterinary applications. Comprehensive testing includes identification, assay, impurity profiling, and specific tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	95.0% - 102.0% (on anhydrous basis)
pH (5% solution)	4.5 - 7.0
Water (Karl Fischer)	≤ 8.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Sterility (if claimed)	Sterile
Bacterial Endotoxins	< 0.25 EU/mg (if for injectable use)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.