Description

4-Chloro-6,7-Dihydro-5H-Cyclopentapyrimidin-2-Ylamine is a high-purity, versatile pyrimidine derivative building block essential for advanced organic synthesis. This compound matters because it serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, enabling the creation of complex molecular architectures. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors and other small molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Employed as a scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies.
• Material Science: Potential precursor for the synthesis of specialty polymers or organic electronic materials.
• Contract Research & Manufacturing (CRAM): Supplied to organizations engaged in custom synthesis and process optimization.

Basic Information

Product Name	4-Chloro-6,7-Dihydro-5H-Cyclopentapyrimidin-2-Ylamine
CAS No.	5461-89-2
Molecular Formula	C7H8ClN3
Molecular Weight	169.61 g/mol
Synonyms	2-Amino-4-chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine; 4-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-amine; 2-Amino-4-chloro-5,6-cyclopentapyrimidine; 4-Chloro-2-amino-6,7-dihydro-5H-cyclopentapyrimidine; 5461-89-2; 4-Chloro-2-cyclopentapyrimidinamine; 4-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7-Dihydro-5H-Cyclopentapyrimidin-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.