Description

2-Amino-6-(Hydroxymethyl)-5,6,7,8-Tetrahydro-1H-Quinazolin-4-One is a versatile, high-purity heterocyclic building block with significant synthetic utility. This compound is valued for its role as a key intermediate in the development of complex pharmaceutical molecules and advanced organic materials. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing libraries of compounds in structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic core.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploratory organic synthesis in academic and industrial research settings.

Basic Information

Item	Detail
Product Name	2-Amino-6-(Hydroxymethyl)-5,6,7,8-Tetrahydro-1H-Quinazolin-4-One
CAS No.	5452-19-7
Molecular Formula	C9H13N3O2
Molecular Weight	195.22 g/mol
Synonyms	6-(Hydroxymethyl)-2-amino-5,6,7,8-tetrahydroquinazolin-4(1H)-one; 2-Amino-6-(hydroxymethyl)-5,6,7,8-tetrahydro-4(1H)-quinazolinone; 2-Amino-6-(hydroxymethyl)-5,6,7,8-tetrahydroquinazolin-4(1H)-one; Tetrahydroquinazolinone derivative; Aminohydroxymethyltetrahydroquinazolinone
EINECS	Contact for details

Quality Control

Our production of 2-Amino-6-(Hydroxymethyl)-5,6,7,8-Tetrahydro-1H-Quinazolin-4-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released according to established in-house specifications, which are aligned with industry best practices for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.