Description

Butyl 2,4-Dioxo-5,6,7,8-Tetrahydro-1H-Quinazoline-6-Carboxylate is a high-purity, synthetic organic compound belonging to the quinazoline class, serving as a critical advanced intermediate for complex chemical synthesis. Its value lies in providing a versatile and reactive scaffold for constructing more complex molecules in research and development. This product is essential for pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive quinazoline core structure.
• Organic Synthesis & Material Science: Acts as a versatile precursor for creating complex heterocyclic compounds, ligands for catalysis, and specialty polymers.
• Biochemical Research: Employed as a reference standard or a starting material for synthesizing enzyme inhibitors and other biochemical probes in life science research.

Basic Information

Product Name	Butyl 2,4-Dioxo-5,6,7,8-Tetrahydro-1H-Quinazoline-6-Carboxylate
CAS No.	5437-56-9
Molecular Formula	C₁₃H₁₆N₂O₄
Molecular Weight	264.28 g/mol
Synonyms	6-Butoxycarbonyl-5,6,7,8-tetrahydroquinazoline-2,4(1H,3H)-dione; Butyl 5,6,7,8-tetrahydro-2,4-dioxo-1H-quinazoline-6-carboxylate; 6-Carboxybutyl 5,6,7,8-tetrahydro-2,4-dioxo-1H-quinazoline-6-carboxylate (alternative ester representation); Tetrahydroquinazoline-dione butyl ester; BTDQC; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our Butyl 2,4-Dioxo-5,6,7,8-Tetrahydro-1H-Quinazoline-6-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.