Description

7-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carboxylic Acid Ethyl Ester is a high-purity, heterocyclic organic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its fused pyridopyrimidine core structure makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated system.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and chemical tools for biological research.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in heterocyclic chemistry and the exploration of new synthetic pathways.

Basic Information

Product Name	7-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carboxylic Acid Ethyl Ester
CAS No.	5435-82-5
Molecular Formula	C12H12N2O3
Molecular Weight	232.24 g/mol
Synonyms	Ethyl 7-Methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylate; 4H-Pyrido[1,2-a]pyrimidine-3-carboxylic acid, 7-methyl-4-oxo-, ethyl ester; 7-Methyl-4-oxo-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid ethyl ester; Ethyl 7-methyl-4-oxopyrido[1,2-a]pyrimidine-3-carboxylate; 5435-82-5; UNII-9J8F8YV8JI; SCHEMBL11827527; DTXSID60652960
EINECS	Contact for details

Quality Control

Our production of 7-Methyl-4-Oxo-4H-Pyrido[1,2-A]Pyrimidine-3-Carboxylic Acid Ethyl Ester adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles against agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.