Description

2-Chloro-4-Piperidin-1-Yl-Pyrimidine is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science: Potential building block for advanced organic electronic materials and liquid crystals.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects and scale-up activities.

Basic Information

Product Name	2-Chloro-4-Piperidin-1-Yl-Pyrimidine
CAS No.	5429-00-5
Molecular Formula	C9H12ClN3
Molecular Weight	197.66 g/mol
Synonyms	2-Chloro-4-(1-piperidinyl)pyrimidine; 4-(Piperidin-1-yl)-2-chloropyrimidine; 2-Chloro-4-piperidin-1-ylpyrimidine; 2-Chloro-4-(piperidino)pyrimidine; Pyrimidine, 2-chloro-4-(1-piperidinyl)-; 5429-00-5; 2-Chloro-4-piperidinopyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Piperidin-1-Yl-Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. Certificates of Analysis (COA) are available for every batch and provided upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.