Description

3,5,6-Trifluoro-2-Nitroaniline is a high-purity fluorinated aromatic amine building block, distinguished by its unique substitution pattern. This compound is valued for its role as a critical intermediate in the synthesis of advanced agrochemicals and pharmaceutical active ingredients. It is primarily sought by research and development chemists and process engineers in the fine chemical, agrochemical, and pharmaceutical manufacturing sectors for constructing complex molecules with specific biological activity.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides and pesticides, where the trifluoro and nitro groups contribute to bioactivity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting various disease pathways.
• Dye and Pigment Synthesis: Serves as an intermediate in the production of specialized dyes and pigments, where its structure influences color fastness and spectral properties.
• Material Science Research: Employed in the development of advanced materials, such as liquid crystals and organic semiconductors, due to its electron-withdrawing substituents.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to introduce anilino groups into complex molecular architectures.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on fluorine chemistry and nitroarene transformations.

Basic Information

Product Name	3,5,6-Trifluoro-2-Nitroaniline
CAS No.	5415-62-3
Molecular Formula	C6H3F3N2O2
Molecular Weight	192.10 g/mol
Synonyms	2-Nitro-3,5,6-trifluoroaniline; 3,5,6-Trifluoro-2-nitrobenzenamine; 2-Amino-3,5,6-trifluoronitrobenzene; 1-Amino-2-nitro-3,5,6-trifluorobenzene; Benzenamine, 3,5,6-trifluoro-2-nitro-; 3,5,6-Trifluoro-2-nitro-phenylamine; TFA Nitroaniline derivative
EINECS	Contact for details

Quality Control

Our 3,5,6-Trifluoro-2-Nitroaniline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. This material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.