Description

7-Chloro-3-Methyl-1H-Pyrazolo[4,3-D]Pyrimidine is a high-value heterocyclic organic compound, recognized as a key synthetic intermediate in advanced pharmaceutical research and development. Its core value lies in its versatile pyrazolopyrimidine scaffold, which is a privileged structure for designing potent and selective kinase inhibitors. This compound is essential for medicinal chemists and process development scientists working in oncology, inflammation, and other therapeutic areas requiring targeted small molecule drugs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel kinase inhibitors targeting various disease pathways.
• Biochemical Research: Used as a core scaffold in structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Agrochemical Development: Serves as a precursor in the research of new active ingredients for crop protection.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new chemical entities.
• Process Chemistry: Employed in route scouting and scale-up optimization for API (Active Pharmaceutical Ingredient) manufacturing.

Basic Information

Product Name	7-Chloro-3-Methyl-1H-Pyrazolo[4,3-D]Pyrimidine
CAS No.	5399-95-1
Molecular Formula	C6H5ClN4
Molecular Weight	168.58 g/mol
Synonyms	7-Chloro-3-methyl-1H-pyrazolo[4,3-d]pyrimidine; 3-Methyl-7-chloro-1H-pyrazolo[4,3-d]pyrimidine; 7-Chloro-3-methyl-1H-1,2,3a,7-tetraazaindene; 7-Chloro-3-methylpyrazolo[4,3-d]pyrimidine; 1H-Pyrazolo[4,3-d]pyrimidine, 7-chloro-3-methyl-; 5399-95-1; 7-Chloro-3-methyl-1H-pyrazolo(4,3-d)pyrimidine
EINECS	Contact for details

Quality Control

Our 7-Chloro-3-Methyl-1H-Pyrazolo[4,3-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.