Description

4-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its role as a versatile and reactive intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Serves as a core scaffold for designing chemical probes and tool compounds to study biological pathways.
• Material Science: Potential building block for organic electronic materials and functional polymers.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule development.
• Academic Research: Used in university and institutional labs for methodological development and discovery chemistry.

Basic Information

Product Name	4-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	5399-92-8
Molecular Formula	C5H3ClN4
Molecular Weight	154.56 g/mol
Synonyms	4-Chloro-1H-pyrazolo[3,4-d]pyrimidine; 4-Chloro-1H-1,2,3-triazolo[4,5-d]pyrimidine (obsolete); 4-Chloro-7H-pyrazolo[3,4-d]pyrimidine; 4-Chloro-1H-1,2,3-triazolopyrimidine; 4-Chloro-1H-pyrazolopyrimidine; 5399-92-8; 4-Chloro-1H-pyrazolo(3,4-d)pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure batch-to-batch consistency and compliance with customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to exclude moisture and stored away from direct light sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.