Description

2-Hydroxy-6-Methyl-4-Phenyl-1,4-Dihydro-Pyrimidine-5-Carboxylic Acid Ethyl Ester is a high-purity, versatile dihydropyrimidine derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a critical synthetic intermediate and scaffold in the development of novel active pharmaceutical ingredients. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry. Our supply ensures consistent quality and reliable availability for your most demanding synthesis projects.

Application

• Pharmaceutical Intermediate: Serves as a core building block for the synthesis of calcium channel blockers and other bioactive molecules.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis: Acts as a key precursor in multi-step synthetic routes for complex heterocyclic compounds.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	2-Hydroxy-6-Methyl-4-Phenyl-1,4-Dihydro-Pyrimidine-5-Carboxylic Acid Ethyl Ester
CAS No.	5395-36-8
Molecular Formula	C14H16N2O3
Molecular Weight	260.29 g/mol
Synonyms	Ethyl 2-Hydroxy-6-methyl-4-phenyl-1,4-dihydropyrimidine-5-carboxylate; Ethyl 4-Phenyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate; 5-Carbethoxy-6-methyl-4-phenyl-1,4-dihydropyrimidin-2-one; 4-Phenyl-6-methyl-3,4-dihydropyrimidin-2(1H)-one-5-carboxylic acid ethyl ester; Biginelli Compound Derivative; DHPM Ester
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-Methyl-4-Phenyl-1,4-Dihydro-Pyrimidine-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your compliance needs in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.