Description

4,4,6-Trimethyl-3,4-dihydropyrimidine-2(1H)-thione is a versatile heterocyclic thiourea derivative with significant utility in organic synthesis and pharmaceutical research. This compound serves as a key synthetic intermediate and building block for the development of novel chemical entities. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly those containing the dihydropyrimidine (DHPM) scaffold, which is associated with diverse biological activities.
• Agrochemical Research: Used in the development and synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core structure.
• Organic Synthesis Reagent: Acts as a versatile precursor or reactant in multi-step synthetic routes for creating complex heterocycles and functionalized molecules.
• Chemical Biology Probe: Employed in research to study enzyme inhibition or as a molecular scaffold for developing biochemical tools and sensors.
• Material Science Research: Investigated as a potential monomer or additive in the development of specialized polymers and advanced materials.

Basic Information

Product Name	4,4,6-Trimethyl-3,4-dihydropyrimidine-2(1H)-thione
CAS No.	5392-23-4
Molecular Formula	C7H12N2S
Molecular Weight	156.25 g/mol
Synonyms	4,4,6-Trimethyl-2-thioxo-1,2,3,4-tetrahydropyrimidine; 4,4,6-Trimethyl-2-mercapto-3,4-dihydropyrimidine; 2-Mercapto-4,4,6-trimethyl-3,4-dihydropyrimidine; NSC 403697; 3,4-Dihydro-4,4,6-trimethyl-2(1H)-pyrimidinethione; 4,4,6-Trimethyl-2-thioxo-1,2,3,4-tetrahydropyrimidine; 4,4,6-Trimethyl-2-thioxo-dihydropyrimidine
EINECS	226-385-9

Quality Control

Our 4,4,6-Trimethyl-3,4-dihydropyrimidine-2(1H)-thione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.