Description

1(2H)-Pyrimidineacetamide, 3,4-Dihydro-2,4-Dioxo- is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce novel pyrimidine-based functionalities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the dihydropyrimidinedione scaffold is pharmacologically active.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators that incorporate heterocyclic motifs for enhanced efficacy.
• Fine Chemical Production: Serves as a versatile building block for creating complex, high-value specialty chemicals used in materials science and catalysis.
• Biochemical Research: Employed as a standard or reagent in biochemical studies to investigate enzyme inhibition and metabolic pathways.
• Academic & Industrial R&D: Fundamental material for methodological development in organic chemistry and for scaling up novel synthetic routes.

Basic Information

Product Name	1(2H)-Pyrimidineacetamide, 3,4-Dihydro-2,4-Dioxo-
CAS No.	5358-14-5
Molecular Formula	C6H7N3O3
Molecular Weight	169.14 g/mol
Synonyms	3,4-Dihydro-2,4-dioxo-1(2H)-pyrimidineacetamide; 2,4-Dioxo-3,4-dihydro-1(2H)-pyrimidineacetamide; 1(2H)-Pyrimidineacetamide, 3,4-dihydro-2,4-dioxo-; 2,4-Dioxo-1,2,3,4-tetrahydropyrimidine-5-acetamide; 5-Carbamoylmethyluracil; 5-(Aminocarbonylmethyl)uracil; NSC 163049; Uracil-5-acetamide
EINECS	226-324-8

Quality Control

Our 1(2H)-Pyrimidineacetamide, 3,4-Dihydro-2,4-Dioxo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.