Description

Amino Acid Hydroxamates Glycine Hydroxamate is a high-purity, specialized chelating agent derived from the amino acid glycine. This compound is valued for its strong metal-binding affinity, making it a critical intermediate in the development of pharmaceuticals, analytical reagents, and industrial chelators. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and chemical synthesis sectors for applications requiring precise metal ion sequestration or inhibition of metalloenzymes.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel hydroxamic acid-based drugs, including histone deacetylase (HDAC) inhibitors and antimicrobial agents.
• Biochemical Research: Used as a potent inhibitor of metalloproteases and other metal-dependent enzymes in biochemical assays and pathway studies.
• Analytical Chemistry: Serves as a selective chelating agent in spectrophotometric methods for the detection and quantification of transition metal ions.
• Industrial Chelation: Employed in water treatment formulations and specialty cleaning products to control scale and sequester problematic metal ions.
• Agrochemical Development: Investigated as a component in the synthesis of novel plant growth regulators or micronutrient delivery systems.
• Cosmetic Ingredients: Potential use in stabilizing formulations by chelating trace metals that can catalyze oxidation in personal care products.

Basic Information

Product Name	Amino Acid Hydroxamates Glycine Hydroxamate
CAS No.	5349-80-4
Molecular Formula	C2H6N2O2
Molecular Weight	90.08 g/mol
Synonyms	Glycine Hydroxamic Acid; N-Hydroxyglycine; Aminoacetohydroxamic Acid; Hydroxyaminoacetamide; Acetohydroxamic Acid, Amino-; Glycine, N-hydroxy-; 2-(Hydroxyamino)acetamide; NSC 112907
EINECS	226-309-3

Quality Control

Our Glycine Hydroxamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment. We adhere to cGMP principles where applicable to support our clients in pharmaceutical and high-purity industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and tendency to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.