Description

1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine,n-(2-Chlorophenyl)-1-Methyl- is a high-purity heterocyclic organic compound, recognized as a key pharmaceutical intermediate and research chemical. Its value lies in its precise molecular structure, which serves as a critical building block for the synthesis of advanced active pharmaceutical ingredients (APIs). This product is essential for R&D laboratories and manufacturing facilities in the pharmaceutical and biotechnology sectors, particularly those developing targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted small-molecule therapies.
• Biochemical Research: Used as a reference standard and building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• API Development: Serves as a core scaffold in the development and scale-up production of Active Pharmaceutical Ingredients (APIs).
• Life Science Reagents: Employed in the preparation of specialized reagents and probes for cellular and enzymatic assays.

Basic Information

Product Name	1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine,n-(2-Chlorophenyl)-1-Methyl-
CAS No.	5334-68-9
Molecular Formula	C12H10ClN5
Molecular Weight	259.69 g/mol
Synonyms	N-(2-Chlorophenyl)-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 4-Amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidine, N-(2-chlorophenyl)-; 1-Methyl-N-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; AG-490 (Typhostin AG 490); Tyrphostin AG 490; NSC 364830; EGFR Inhibitor AG490; Janus Kinase 2 Inhibitor AG490
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine,n-(2-Chlorophenyl)-1-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.