Description

6-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-4(7H)-One is a high-purity heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its value lies in its versatile pyrazolopyrimidine scaffold, which is a privileged structure for designing potent and selective bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on kinase inhibitor discovery and nucleoside analog development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel kinase inhibitors targeting oncology, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides due to its bioactive heterocyclic core.
• Nucleoside Analog Synthesis: Serves as a precursor for modified nucleosides with potential antiviral or anticancer activity.
• Chemical Biology Probes: Utilized in medicinal chemistry to create tool compounds for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of targeted Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
• Academic & Institutional Research: Provides a foundational scaffold for universities and research institutes exploring new chemical entities.

Basic Information

Product Name	6-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-4(7H)-One
CAS No.	5334-35-0
Molecular Formula	C7H5ClN4O
Molecular Weight	196.59 g/mol
Synonyms	6-Chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol; 6-Chloro-1-methyl-7H-pyrazolo[3,4-d]pyrimidin-4-one; 4(7H)-Pyrimidinone, 6-chloro-1-methyl-1H-pyrazolo[3,4-d]-; 6-Chloro-1-methyl-1,7-dihydropyrazolo[3,4-d]pyrimidin-4-one; 1-Methyl-6-chloro-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-4(7H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding R&D and scale-up processes. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity profiles and impurity characterization. Our quality commitment aligns with ICH guidelines, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.