Description

4-Amino-6-Chloropyrimidine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a chloro substituent on the pyrimidine ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of nucleoside analogs, kinase inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized dyes and optical brighteners.
• Material Science: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Amino-6-Chloropyrimidine
CAS No.	5305-59-9
Molecular Formula	C4H4ClN3
Molecular Weight	129.55 g/mol
Synonyms	6-Chloro-4-pyrimidinamine; 4-Pyrimidinamine, 6-chloro-; 6-Chloro-4-aminopyrimidine; 4-Amino-6-chloro-1,3-diazine; NSC 403697; A6CP
EINECS	226-154-5

Quality Control

Our 4-Amino-6-Chloropyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	185 - 190 °C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.