Description

4,6-Dichloropyrimidine-5-carbonitrile is a versatile and highly functionalized pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive chlorination and nitrile groups, which enable precise molecular construction for complex target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other biologically active heterocyclic compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Acts as a monomer or cross-linking agent in the creation of specialized polymers and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring complex pyrimidine scaffolds.

Basic Information

Product Name	4,6-Dichloropyrimidine-5-carbonitrile
CAS No.	5305-45-3
Molecular Formula	C5HCl2N3
Molecular Weight	173.99 g/mol
Synonyms	5-Cyano-4,6-dichloropyrimidine; 4,6-Dichloro-5-pyrimidinecarbonitrile; 4,6-Dichloro-5-cyanopyrimidine; 5-Pyrimidinecarbonitrile, 4,6-dichloro-; 4,6-Dichloropyrimidine-5-carbonitrile; 2,4-Dichloropyrimidine-5-carbonitrile (common misnomer); 4,6-Dichloro-5-cyano-pyrimidine
EINECS	226-158-8

Quality Control

Our 4,6-Dichloropyrimidine-5-carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.