Description

4,6-Dichloro-5-(1,3-Dioxolan-2-Yl)Pyrimidine is a versatile and high-value pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its primary commercial value lies in its role as a key synthetic intermediate for the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with specific biological activities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside analogs, antiviral agents, and other complex heterocyclic APIs.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and specialty polymers requiring pyrimidine scaffolds.
• Research & Development: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing tailored compounds for client projects.

Basic Information

Product Name	4,6-Dichloro-5-(1,3-Dioxolan-2-Yl)Pyrimidine
CAS No.	5305-44-2
Molecular Formula	C7H6Cl2N2O2
Molecular Weight	221.04 g/mol
Synonyms	5-(1,3-Dioxolan-2-yl)-4,6-dichloropyrimidine; 4,6-Dichloro-5-(1,3-dioxolan-2-yl)pyrimidine; 4,6-Dichloro-5-(2',2'-dimethyl-1,3-dioxolan-4'-yl)pyrimidine (related); 2-(4,6-Dichloropyrimidin-5-yl)-1,3-dioxolane; Pyrimidine, 4,6-dichloro-5-(1,3-dioxolan-2-yl)-; 5305-44-2 (CAS); DDP Intermediate
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-5-(1,3-Dioxolan-2-Yl)Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.