Description

6-Chloro-4-oxo-1,4-dihydropyrimidine-5-carbonitrile is a versatile and high-value heterocyclic building block in organic synthesis. This compound matters as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). Pharmaceutical researchers, agrochemical developers, and fine chemical manufacturers need this precise chemical scaffold to drive innovation in drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside analogs, antiviral agents, and other bioactive pyrimidine derivatives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides that target specific biological pathways.
• Fine Chemical Building Block: Serves as a versatile starting material for creating complex heterocyclic compounds in custom synthesis and contract research.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and biochemical assays exploring nucleotide metabolism.
• Material Science Research: Investigated for the development of novel organic electronic materials and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Chloro-4-oxo-1,4-dihydropyrimidine-5-carbonitrile
CAS No.	5305-43-1
Molecular Formula	C5H2ClN3O
Molecular Weight	155.54 g/mol
Synonyms	5-Cyano-6-chloro-2-hydroxypyrimidine; 6-Chloro-5-cyano-2(1H)-pyrimidinone; 6-Chloro-2-hydroxy-5-cyanopyrimidine; 6-Chloro-5-cyanouracil; 6-Chloro-2-oxo-1,2-dihydropyrimidine-5-carbonitrile; 6-Chlorouracil-5-carbonitrile; 2-Hydroxy-6-chloro-5-cyanopyrimidine; 5-Cyano-6-chlorouracil
EINECS	226-158-5

Quality Control

Our 6-Chloro-4-oxo-1,4-dihydropyrimidine-5-carbonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.